化學名稱：Dextran, hydrogen sulfate sodium salt; Dextran sulphate; Sodium dextran sulfate; Dextran polysulfate
CAS 編號：9011-18-1

硫酸葡聚糖是由特定分子量的葡聚糖硫酸化反應制得的。TdB生產的低取代度硫酸葡聚糖分子量從5 kDa到500 kDa。

硫酸葡聚糖是以鈉鹽形式呈現，并加入少量磷酸鹽作為穩定劑。 每個批次的產品都提供質檢報告COA。嚴格仔細控制分子量程，含硫量，濕度等指標。

葡聚糖是一種多糖，來源于腸系膜明串珠菌B512F，由α-D-(1-6)線性葡聚糖組成，側鏈含量較低（約5%），與葡萄糖的碳-3位相連。硫酸葡聚糖是特定分子量的葡聚糖硫酸化得到的衍生物。低取代度硫酸葡聚糖的硫酸組分在8-13%之間。

圖1。低取代度硫酸葡聚糖片段的結構表征。

硫酸葡聚糖（DS）可按不同平均重均分子量，不同分子量分布，不同程度的取代度，不同陽離子（例如鉀替代鈉）和不同硫酸化過程來生產。例如，僅憑硫酸葡聚糖70的名稱無法完整識別該化合物，在評估這些化合物性能時應考慮到這一點。

硫酸葡聚糖是由選定的葡聚糖片段和硫酸化試劑（例如氯磺酸）合成而來，反應混合物經過純化后，可以獲得白色粉末狀產品。

室溫下，硫酸葡聚糖在干燥密閉的容器內可以保持穩定超過6年。

硫酸葡聚糖涉及廣泛的應用領域和性質。舉例如下

• 細胞培養用的抗凝劑
• 脂蛋白的選擇性淀析
• 加速DNA雜交
• 從DNA-組蛋白復合物中釋放DNA
• 抑制tRNA與核糖體的結合
• 核糖核酸酶抑制劑
• 抗病毒性
• 用于化妝品的抗感染和透水保濕
• 分離微生物和大分子
• 疫苗佐劑
• 膜選擇性滲透研究

產品編號	品名	分子量(kDa)	包裝
DB005-10g	Dextran sulfate 5 LS	5	10 g
DB005-100g			100 g
DB009-10g	Dextran sulfate 10 LS	10	10 g
DB009-100g			100 g
DB013-10g	Dextran sulfate 20 LS	20	10 g
DB013-100g			100 g
DB003-10g	Dextran sulfate 40 LS	40	10 g
DB003-100g			100 g
DB015-10g	Dextran sulfate 100 LS	100	10 g
DB015-100g			100 g
DB051-10g	Dextran sulfate 500 LS	500	10 g
DB051-100g			100 g

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