IL-33 （人）, ELISA 試劑盒 IL-33 (human), ELISA kit

來源：作者：人氣：-發(fā)表時間：2024-08-01 12:44:00【大中小】

IL-33（釋放于壞死細(xì)胞）動員殺傷性Ｔ細(xì)胞應(yīng)對病毒感染

IL-33 （人）, ELISA 試劑盒 IL-33 (human), ELISA kit

◆原理

細(xì)胞死亡后會釋放一類特殊的蛋白質(zhì) Alarmin（暫譯為警報素），通過檢測 Alarmin 可識別組織創(chuàng)傷。然而在抗病毒免疫系統(tǒng)中，Alarmin 所起的作用不是很明確。最近瑞士日內(nèi)瓦大學(xué)和德國柏林夏里特醫(yī)科大學(xué)研究人員發(fā)現(xiàn)在脾臟和淋巴結(jié)中病毒的復(fù)制可導(dǎo)致受感染的細(xì)胞死亡。這些壞死的細(xì)胞可釋放出 Alarmin，其中主要的是白介素-33（IL-33），它可通過 ST2 受體激活 CD8+ T（CTLs）細(xì)胞，對病毒感染作出反應(yīng)。研究發(fā)現(xiàn)缺乏 IL-33 的小鼠，CTL 對病毒感染的免疫反應(yīng)也較低。此項研究具有里程碑意義，因為提出了一個新的免疫機制：壞死細(xì)胞會釋放出 Alarmin 動員殺傷性Ｔ細(xì)胞應(yīng)對感染，在未來對抗艾滋、丙型肝炎而開發(fā)新的疫苗，對于癌癥治療有重要作用。

Enzo Life Sciences 提供大量細(xì)胞壞死研究用產(chǎn)品，先天性免疫適應(yīng)性免疫等。許多與 Alarmin IL-33 有關(guān)，供科研人員選擇。

◆優(yōu)點?特色

產(chǎn)品名稱	特點
IL-33 (human), ELISA kit	Reliably measure as little as 1.7 pg/mL of IL-33
IL-33 (mouse) ELISA Kit	Reliably measure as little as 10pg/mL of IL-33
IL-33 soluble (human), detection set	Reliably measure as little as 5pg/mL of IL-33
GFP-Certified™ Apoptosis/Necrosis detection kit	Cell-based assay for microscopy and flow cytometry
IL-33 (human), (recombinant)	≥95% pure (SDS-PAGE)
IL-33 (human), (recombinant)	≥95% pure (SDS-PAGE), FLAG-tag
IL-33 (human), (recombinant)	≥95% pure (SDS-PAGE), His-tag
Pro-IL-33 (human), (recombinant)	≥90% pure (SDS-PAGE), His-tag
IL-33 (human) (homeodomain-like helix-turn-helix), (recombinant)	Human IL-33 homeodomain, fused at C- terminus to His-tag, ≥95% pure (SDS-PAGE)
IL-33 (mouse), (recombinant)	≥95% pure (SDS-PAGE)
IL-33 (mouse), (recombinant)	≥95% pure (SDS-PAGE), His-tag
IL-33 (rat), (recombinant)	≥95% pure (SDS-PAGE)
IL-33 (human), mAb	Suitable for ELISA, IHC, IP, WB (clone IL33305B)
IL-33 (human), pAb	Suitable for ELISA, WB
IL-33 (human), pAb	Suitable for ELISA, WB, Biotin conjugate
IL-33 (mouse), pAb	Suitable for ELISA, WB
L-33, mAb	Recognizes human and mouse IL-33. ELISA, IP, WB.(clone IL33026B)
IL-33, mAb	Recognizes human IL-33. Weakly cross-reacts with mouse IL-33. ELISA, WB. (clone IL33068A)
L-33, mAb	Recognizes human, mouse and rat pro-IL-33 (precursor) and mature IL-33. ELISA, IHC, IHC, IP, WB (clone Nessy-1)
IL-33, mAb	Biotin-conjugate (clone Nessy-1)
IL-33, mAb	Preservative free, (clone Nessy-1)
IL-33, mAb	ICC, WB (clone Nessy-2)
IL-33, pAb (AT110)	Recognizes human, mouse and rat pro-IL-33 and mature IL-33, ELISA, WB
IL-33, pAb (AT110)	Biotin-conjugate
ST2 (human), (recombinant)	≥90% pure (SDS-PAGE)
ST2 (human), mAb	ELISA, IHC, IHC, WB (clone ST33868)
ST2 (human):Fc (human), (recombinant)	≥90% pure (SDS-PAGE)
ST2 (mouse):Fc (human), (recombinant)	≥95% pure (SDS-PAGE)
IL-1RAcP (human):Fc (human) (recombinant)	Forms heterodimer complex with ST2 to make the IL-33 receptor. ≥95% pure (SDS-PAGE)